灌注系統(tǒng)概述

HSE—HA生理學(xué)系統(tǒng)是一系列應(yīng)用廣泛的完備產(chǎn)品，可用于整體動物生理學(xué)、立體或在體器官和組織灌注及組織浴槽研究。這些系統(tǒng)具有廣泛的應(yīng)用，包括傳統(tǒng)的安全藥理學(xué)、DMPK、毒理學(xué)、呼吸系統(tǒng)、心臟病學(xué)、分子生物學(xué)和生理學(xué)。每個(gè)系統(tǒng)都設(shè)計(jì)了標(biāo)準(zhǔn)的組件，再加一些其他配置以適合特殊研究的需要。。標(biāo)注組件也意味著如果你是需要將現(xiàn)有設(shè)備配齊，或者進(jìn)行系統(tǒng)升級，或者是完整的配套產(chǎn)品，你都只需要購買需要的構(gòu)件。HSE-HA生理學(xué)系統(tǒng)為你提供各種工具，使你的研究走向多產(chǎn)和成功。

我們提供大多數(shù)生理學(xué)檢測設(shè)備，包括放大器、電極、傳感器和電化學(xué)檢測器。參數(shù)包括力、位移、壓力、液體和氣體流、心電圖(單導(dǎo)聯(lián)—12導(dǎo)聯(lián)系統(tǒng))、MAP(單個(gè)或多個(gè)部位)、腦電圖、肌電圖、連續(xù)支流灌注傳統(tǒng)的血?dú)鈪?shù)和電解質(zhì)的分析，可以選擇程序化軟件和傳統(tǒng)的刺激器作為放大器、電極和傳感器等產(chǎn)品的補(bǔ)充。

HSE-DAQ系統(tǒng)產(chǎn)品家族(BDAS、ACAD、HAEMODYN、ISOHEART、PULMODYN、PENNOCK)可以記錄你的初始信號，計(jì)算到處的參數(shù)，注釋數(shù)據(jù)，快速簡易的輸入確定的數(shù)據(jù)用于分析。同時(shí)還可以選擇用于進(jìn)一步分析的軟件模塊，帶狀記錄紙打印，自動和控制模塊等。產(chǎn)品經(jīng)過預(yù)先設(shè)置，打開包裝即可使用，并專門設(shè)計(jì)符合你的系統(tǒng)配置和數(shù)據(jù)分析要求。

• Applications:

– Evaluation of metabolites or mediators released on subsequent tissues in the fluid cascade

– Detection of substances affecting the smooth musculature (prostaglandins, bradykinin, angiotension II...)

• Suitable for colon, bladder, ileum, duodenum, aortic strips...

• Low volume superfusion is useful when only small quantities of drugs are available

• No contact with glass, surface-active substances cannot be absorbed on the glass surface and contaminate results

The Superfusion Cascade Bath permits testing of extremely small quantities of pharmaceuticals. Any metabolites or mediators released are passed to the subsequent test preparation and can become effective there. It is possible to test up to four preparations (muscle strips or isolated tissues). The preparations are contained in a thermostated chamber. A roller pump produces a small flow of solution (1 – 10 ml/min) which is warmed by a heat exchanger then drips on to the uppermost test preparation. There is a provision for switching between two different solutions. The effluate of each preparation passes in the form of a cascade onto the subsequent preparation. Any muscle contractions produced are measured by force transducers (isometric contraction measurement) or displacement transducers (isotonic contraction measurement).

The Superfusion Cascade Bath, as modified by SCHULER, consists of a moist acrylate chamber which is thermostated by radiant heat from a thermostated metal plate. Temperature control is provided by a thermostatic circulator. The four tissues are arranged in cascade so that each tissue receives its superfusion solution from the previous tissue through a small tube. These stainless steel tubes carry a ring to which the tissues are attached. Part of the tube is in the form of an open channel. The tubes can be moved in height (vertically) and also horizontally, ensuring optimum adjustment to suit the suspended tissues and allows superfusion free from any interruption. Mounting the tissues is simplified by the removable front panel of the chamber.