Compared to similar stains, the more finely controlled colloidal structure of ProtoBlue Safe improves both the sensitivity and the universality of staining. ProtoBlue Safe is less prone to high background caused by trace residual SDS in the gel.

Laboratories typically spend twice as much per gel in the methanol and acetic acid for staining and destaining with regular Coomassie than for ProtoBlue Safe (including ethanol cost). In addition, ProtoBlue Safe is much faster, more sensitive, and you can pour the used stain solution down the drain. Protein visualization is faster, safer, more sensitive and less-expensive with ProtoBlue Safe.
G-250 Stain膠體考馬斯藍(lán)染色劑